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In 2000, Professor Philip Hogg asked himself a very important question, one that could lead to a powerful
breakthrough treatment for brain and pancreatic cancers and, potentially, cancer as a whole. The question
Professor Philip asked was how do cancers feed themselves? It is well known in the scientific community
that cancer cells hijack normal systems of metabolism to increase their energy.
If researchers can help to discover how to target this process, patients could be treated for the disease
with limited side effects.
Professor Philip and his team may be close to an answer for this ‘big question’ with the development of a
molecule that inhibits the use of sugar in tumours by deactivating a key component of the cell’s energy
factory, or mitochondria. Because this revolutionary new drug targets cancer cells selectively and leaves
other cells alone, Professor Philip believes it could be more effective than chemo and allow patients to
live a relatively normal life during treatment.
Clinical trials of the drug have just begun. If the drug is as successful as the team hopes, it could help
bring people with brain cancer one step closer to cure.